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Proper studies may provide useful information on how COX-2 inhibitors like Vioxx can be used safely.

The evidence showing a strong association between selective COX-2 inhibition (from Vioxx™, Bextra™, or Celebrex™) and risk of heart disease and stroke has been piling on ever since Vioxx™ was removed from the market in the fall of last year. Now, we have studies that get into the nitty-gritty of exactly how COX-2 inhibitors do this. This is useful information because it might lead to clinical tests that help determine the risk-benefit balance of going on COX-2 medication and might even inform dosage.

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Read more from this blogger: How COX-2 inhibitors increase the risk of heart disease and stroke